Lion's mane is a powerful medicinal mushroom with promising benefits for brain health, gut health and nerve regeneration.*How can a mushroom once used by monks as a concentration aid help with modern maladies? Can something with a bizarre moniker like "monkey head mushroom" actually improve brain function, boost mood, promote gut health and encourage nerve growth? Whether it reminds you of a Muppet, a truffula tree or an actual lion, this quirky tooth fungus packs much more of a punch than meets the eye. Dive into this guide to discover how lion's mane mushroom can benefit your health on multiple levels.
What is Lion's Mane Mushroom?
Although its scientific name is Hericium erinaceus, lion's mane has several nicknames in countries around the world. In Japan, it's known as Yamabushitake, or the "mountain priest mushroom;" in China, it's Ho Tou Gu, the "monkey head mushroom." Lion's mane's shaggy appearance has also earned it titles like:- Bearded tooth mushroom
- Bearded hedgehog mushroom
- Bearded tooth fungus
- Satyr's beard
- Pom pom mushroom
A Historical Look at Lion's Mane Mushroom
Like most medicinal mushrooms, lion's mane has a long history of use in Asian cultures, including traditional Chinese medicine. It's still used in China today in pill form as a remedy for gastritis, as well as ulcers of the stomach, esophagus and duodenum*. According to Chinese records, lion's mane mushroom cultivation didn't begin until 1988. Modern cultivation practices vary, with some growing through the entire life cycle and harvesting the whole mushroom, and others skipping a step allowing for cheap, scalable production—often at the expense of quality. (More on this later.)Traditional Lion's Mane Mushroom Benefits
Hericium erinaceus' claim to fame throughout the centuries was its apparent ability to soothe membranes in the digestive tract. Traditionally used to combat digestive distress, and stomach problems lion's mane mushroom was also recognized as a restorative agent for overall health*. The healing, regenerative nature of lion's mane was believed to help support*:[1]- Liver
- Spleen
- Heart
- Lungs
- Kidneys
How to Identify Lion's Mane Mushroom
All the "beard" references in nicknames for lion's mane provide a nearly perfect description; they're not hard to recognize! However, since several species of tooth fungus exist (and not all of them are tasty), it helps to know what makes lion's mane unique. Lion's Mane Fruiting Body Hericium erinaceus grows to be 8 to 16 centimeters (around 3 to 6 inches) in size with fluffy "spines" 1 centimeter (just under 0.4 inches) long.[2] The mushrooms grow in single clumps, with the dangling spines creating a "snowball" appearance.[3] These spines continue to grow as the mushroom ages. Color Fresh, healthy lion's mane specimens are white in color. Browning can be an indication of damage, but it doesn't always mean the mushroom is no longer edible. (It just might not taste as good.) Hericium Varieties Several other mushrooms keep lion's mane company in the Hericium genus:- Hericium americanum, characterized by longer spines
- Hericium coralloides, which grows in "branches" with dangling "hairs"
- Hericium abietis, found in the Pacific Northwest
- Hericium alpestre, a native of Europe
- Hericium cirrhautum, a shell-like variety
Where to Find Lion's Mane Mushroom in the Wild
For aspiring mushroom foragers, Hericium erinaceus is an easy target. Hairy specimens pop up in the late summer and early autumn in North America, Europe and Asia. Where does lion's mane mushroom grow? Look for dead and dying hardwood, particularly fallen logs. Maple, beech, oak, walnut and sycamore can all act as natural substrates. Watch: Hunting Hericium americanum (Bear's Head Tooth) and Hericium coralloides (Coral tooth fungus)Where Can I Buy Lion's Mane Mushroom?
Those who prefer to "hunt" for mushrooms at the grocery store may be able to find fresh lion's mane mushroom for sale at farmers markets, Asian markets and neighborhood co-ops. Local growers are also good sources—and, of course, anyone who knows how to forage and is willing to share. Sourcing mushrooms locally provides the best guarantee of peak freshness, flavor and nutrition. The farther they have to travel, the older they are by the time they hit the shelves, and the more likely they are to be damaged.Can You Grow Lion's Mane Mushroom at Home?
Learning how to grow lion's mane solves the problem of trying to find this often-elusive specimen. Although Hericium erinaceus can take a good while to grow full maturity in the wild, it's possible to grow the mushroom at home in a matter of weeks. A mushroom growing kit is the easiest way to start growing lion's mane. Because the process doesn't need anything special aside from humidity, beginners won't feel overwhelmed by a bunch of complicated cultivation instructions. All that's needed is to set the kit on a countertop and watch the mushrooms grow! Advanced mushroom growers (and anyone up for a little more of a challenge) can start with lion's mane mushroom spawn and a hardwood sawdust substrate. Harvesting Lion's Mane Mushrooms Home-grown specimens are ready for harvest when they've become full "snowballs." All that's needed is to cut them off at the base and brush away any dirt before cooking. One caution: Lion's mane mushrooms bruise easily. Handle with care to avoid damaging the beautiful white fruiting bodies! Related: Mushroom Growing Kits — Complete Guide, Reviews and Top PicksHow Lion's Mane Mushroom Works
Lion's mane contains a variety of functional compounds, but two main players stand out:- Aromatic hericenones
- Diterpenoid erinacines
Lion's Mane Mushroom Benefits: From Brain Health to Better Aging
Okay, so there's a lot of amazing chemistry "behind the scenes," but what is lion's mane mushroom actually good for? Science appears to support several traditional uses for the shaggy mushroom, and research is ongoing. Although the majority of studies have been performed on animals or on cells in petri dishes (in vitro), the results show promising potential for ways lion's mane can benefit human health. Take a look at what research has revealed about the power of Hericium erinaceus.1. Linked to Better Brain Health*
The unique ability of erinacines to cross the blood-brain barrier and promote regenerative activity within the brain is the most-cited perk of using lion's mane mushroom*. Why is this such a big deal? It all comes down to nerve growth factor (NGF). Nerve growth factor functions exactly as the name would suggest: It regulates nerve cell growth and reproduction, maintains cellular health and prevents cell death.[9] NGF is part of a family of molecules known as neurotrophic factors, which support both mature and developing neurons.[10] Neurotrophic factors make it possible for the brain to heal and repair itself after injury and maintain what's known as "plasticity" throughout life. In other words, NGF is one of the reasons why you can teach an old dog (or, in this case, human) new tricks. Your brain never stops responding to information, thought patterns and outside stimuli, and NGF helps to strengthen—or even create—important neural pathways in the brain.[11] But there's a weird catch. NGF itself isn't capable of crossing the blood-brain barrier; the molecule is too big. This isn't a problem in healthy individuals whose brains make enough NGF. When the brain begins to age, however, levels of NGF and other neurotrophic factors decline. That's where Hericium erinaceus comes in. Extracts from the mushroom have the potential to enhance the growth of neurites*. These projections grow out of nerve cells and become either axons or dendrites—the parts of neurons that allow the cells to communicate with each other. More neurite growth (or regeneration) means better communication and better overall brain function. Lion's Mane and Dementia Problems with cognition can arise when the brain fails to keep up with growing and forming new connections as people age. The resulting cognitive decline can manifest as varying degrees of memory loss or dementia. Several studies have shown the potential of lion's mane for dementia prevention and cognitive support*:- A group of 30 older adults with "mild cognitive impairment" were split into two groups and given either lion's mane or a placebo. Those supplementing with lion's mane performed better on cognitive tests at week 8, 12 and 16 of the study*.[12]
- In studies on PC12 cells—used to study brain health and function—lion's mane appears to prevent damage and reduce the occurrence of cell death*.[13,14]
- Even in healthy subjects,[15] mushroom supplementation may enhance the ability to recognize and recall previously learned information ("recognition memory") by exerting activity similar to brain-derived neurotrophic factor (BDNF)*.[16] BDNF supports neuronal plasticity, making learning, memorization and recall easier.[17]
- Hericium erinaceus extracts improved memory and reduced Alzheimer's symptoms in rat studies*[19]
- The mushroom may up-regulate an anti-inflammatory molecule known as lipoxin A4 within the brain, leading to a reduction in inflammation-related damage suspected of playing a role in cognitive decline*[20]
- In a mouse model of Alzheimer's, erinacine-A-enriched lion's mane mycelia showed anti-plaque activity and promoted both NGF and its precursor, leading to neurogenesis (nerve growth) in the hippocampus*[21]
2. Depression and Anxiety*
Lion's mane isn't only a powerhouse for memory—it may also help with mood. Extracts of Hericium erinaceus appear to regenerate cells in the hippocampus, the area of brain responsible for emotional response and memories*.[23]. In a mouse model, the mushroom showed potential to support neurogenesis, the process of growing new nerve cells*. The practical daily benefit of all this can be seen in studies relating to anxiety and depression. A four-week trial involving a group of 30 post-menopausal women found that cookies made with lion’s mane won out over placebo cookies for reducing anxiety and irritability*.[24] Lion's mane extracts have been shown to block the signalling power of nuclear factor kappa beta (NF-kB), a protein complex responsible for promoting inflammation by inducing synthesis of pro-inflammatory compounds*. The mushroom can also reduce elevated levels of two pro-inflammatory cytokines known as IL-6 and TNF-alpha.[25] Because inflammation may play a role in some mood disorders, these actions could offer significant benefits for people struggling with anxiety and depression*. One other thing of note: Lion's mane mushrooms contain GABA, an inhibitory neurotransmitter that induces relaxation and may have anti-depressant effects*.[26] Concentrations can be increased by boiling the mushroom and fermenting the resulting juice.[27] However, this particular property hasn't yet been tested in relationship to mood disorders.3. Heart Health*
Studies have shown that lion's mane may be able to increase HDL cholesterol, lower both LDL and triglycerides and reduce the amount of cholesterol the body makes*. In addition, a natural polymer from the mycelium appears to be able to lower the atherogenic index, an indicator of overall cardiac risk*.[34] In an in vitro study, one specific Hericium erinaceus fraction out of five was shown to be "the most potent" inhibitor of LDL oxidation and cholesterol synthesis*. This suggests the potential to reduce cholesterol oxidation that leads to plaquing—and, therefore, prevent blood vessels from narrowing*.[35] Lion's mane may even prevent the body from metabolizing fats from high-fat foods*.[36] Taken together, these activities could provide protection against some of the most significant drivers of heart disease, a malady so prevalent in developed nations that arterial plaques have been discovered in babies prior to birth*.[37,38]4. Inflammation*
Inflammation is coming to the forefront as a prominent factor in numerous chronic diseases. This is likely due to the slow, steady damage induced by inflammation at a cellular level. In cases where ongoing low-grade stress is an issue, this damage can affect any system in the body, thus setting the stage for disease. Lion's mane fruiting body extracts have demonstrated potent antioxidant activity, which is just what the body needs when faced with chronic inflammation*.[39] Antioxidant Power of Lion's Mane Mushrooms When the body is stressed or exposed to chemicals—whether in the environment or food—compounds known as free radicals form. Free radicals are missing electrons and will "scavenge" electrons from healthy cells to achieve stability, which touches off an inflammatory cascade that can lead to damage. Over time, this damage causes changes associated with aging, which often include chronic disease. Antioxidants like those found in lion's mane have the ability to "donate" electrons to free radicals, which neutralizes the compounds while protecting healthy cells*. The result? Less inflammation and a lower risk of cellular damage*.[40] According to research, lion's mane may have specific benefits related to this anti-inflammatory activity*, including:- Reducing skin aging by boosting levels of skin antioxidants and collagen proteins*[41]
- Reducing pro-oxidant reactive oxygen species (ROS) and increasing antioxidant levels in the brain*[42]
- Boosting antioxidants and reducing lipid peroxidation in diabetic rat models,[43] which suggests potential applications for managing diabetic neuropathy*
5. Lion’s Mane and Diabetes*
What about lion's mane for diabetes*? The current body of scientific evidence suggests this mushroom has benefits beyond its anti-inflammatory activities in cases of metabolic syndrome*. Research in diabetic animal models shows:- Potential anti-hyperglycemic effects*[46]
- The ability to increase insulin levels and reduce lipids in the bloodstream*[47]
- Antioxidant activity; reduced inflammation; and regulation of HbA1c, insulin and plasma glucose levels*[48]
6. Immune Activity*
Lion's mane is associated with stronger immune system activity, a characteristic it shares with several other medicinal mushrooms*. It appears to affect immunity by:- Boosting innate immune activity to protect against bacterial pathogens*[49]
- Exerting anti-inflammatory and anti-cancer effects*
- Boosting natural killer cell activity, enhancing antibody-mediated (humoral) and cell-mediated immunity and improving the ability of macrophages to ingest and destroy pathogens*[50]
- Upregulating secretory immunoglobulin A (SIgA), which protects against toxins and pathogens in the intestine*[51]
- Better T-cell proliferation and differentiation, which allows the body to properly target and attack invading pathogens*[54]
- Accurate "training" for the immune system to recognize and eliminate antigens instead of attacking body tissues*[55]
7. Gastric Ulcers*
Here's one traditional use for Hericium erinaceus that gets the thumbs-up from science. More than one study has shown treating gastric ulcers with lion's mane appears to reduce their size*.[57] The mechanisms behind this may include:- Increasing antioxidant activity to protect the gastric mucosal lining from damage*[58]
- Preventing the growth of H. pylori, commonly associated with ulcer formation*
8. Damaged Nerves*
Some of the same properties that make lion's mane mushroom good for brain health may explain why it's been shown to help with recovery from nerve injury, nerve pain (neuropathy) and strokes*. For example, one in vitro study showed lion's mane extract was able to speed up development of the protective myelin sheath around nerves in cultured brain cells while promoting "normal" cell growth*.[60] In another study using animal cells, extracts promoted neurite growth in both brain and spinal cord models*.[61] A study directly addressing nerve injury in rats indicated lion's mane mushrooms have the ability to regenerate nerves and improve recovery, possibly by promoting relevant nerve signaling pathways and axon protein synthesis*.[62,63] Other research using erinacine-enriched lion's mane mycelia to address neurodegeneration in an animal model demonstrated a delay in neuronal cell death and suggested potential for improving recovery from both hearing loss and pain associated with nerve damage*.[64] Demyelination By promoting normal nerve cell growth and supporting myelination, it's possible that extracts from lion's mane mushroom fruiting bodies could help people suffering from multiple sclerosis*.[65] This hasn't officially been studied, but other properties of the mushroom—including its anti-inflammatory activity and ability to promote NGF production—also suggest potential applications in treating or improving this condition*. Lion’s Mane and Parkinsons Brain benefits from Hericium erinaceus appear to go beyond preventing cognitive decline*.- Preventing apoptosis from oxidative stress*
- Inhibiting neuronal cytotoxicity*[66]
9. Could Support Longevity and Well-Being*
For centuries, Eastern cultures have recognized medicinal mushrooms' ability to improve overall health—and many believed these powerful fungi could also lengthen life*. Sounds like the dream of a mystical fountain of youth, right? There might be more to it than that. Oxidative stress from any source creates free radicals in the body. Free radicals running amok leads to cell damage, and cell damage is a big culprit in the aging process. And then there are telomeres. Telomeres are specific sequences at the ends of DNA strands. They can be thought of somewhat like the plastic tips that keep shoelaces from unraveling—because it's the job of telomeres to protect DNA strands from damage.[68] Every time cells divide, though, telomeres get shorter, a process that limits how many times a particular cell line is able to replicate. Oxidative stress can speed up this natural shortening process.[69] (That might explain why it seems like stress accelerates aging—science is starting to show this could actually be the case!) Antioxidant compounds like those found in lion's mane, however, have the potential modulate these effects*.[70] The key here appears to be brain-derived neurotrophic factor. BDNF is known for its role in promoting learning and memory,[71] but it can also regulate telomerase, the enzyme involved in maintaining telomere length.[72] Lion's mane may promote telomerase activity by: Along with the numerous other known and emerging benefits of the mushroom, these factors suggest Hericium erinaceus can make it possible to enjoy a healthy, vibrant life at any age*.What is the Best Lion's Mane Supplement?
Choosing supplements should always be a careful process. Because natural supplements, including medicinal mushrooms, aren't specifically regulated, not every manufacturer is honest about what's in their products. For Hericium erinaceus supplements, it's important to look for products made from whole fruiting bodies. Avoid artificial ingredients, binders, fillers, grains and starches. If mycelium and substrate are listed on the label, it's likely the supplement contains more starch than actual lion's mane. And what's the point of supplementing with starch if the real benefits are in the mushrooms?How Lion's Mane Extract is Made
Medicinal mushroom extracts and powders are made using one of three processes: water extraction, alcohol extraction or dual extraction. In water extraction, mushrooms are simmered in vats of hot water to make a decoction, sort of like strong tea. Alcohol extraction involves soaking mushrooms in alcohol for several weeks. Performing both processes separately and combining the result creates a dual extract, which contains both the water soluble and fat soluble compounds. Here's what it looks like step by step at a company like FreshCap:- Harvest and dry whole lion's mane fruiting bodies
- Mill the dried mushrooms into a fine powder
- Perform a hot water extraction, or alcohol extraction (we do both)
- Use spray drying to turn the extracted liquid into a powder
- Combine the powders if dual extraction was performed
Lion's Mane Mushroom Capsules vs. Powder
Hericium erinaceus is available in capsules, powders and tinctures. The mushroom also appears in functional foods like coffee, elixirs and drink mixes; dried lion's mane can be brewed into tea. The "best" form of lion's mane supplement is whatever form makes sense for a person's lifestyle. Each type has its benefits:- Tinctures are quick and easy to take
- Capsules fit easily into existing supplement regimens
- Powders can be incorporated into a variety of drinks and foods
Does Mushroom Coffee with Lion's Mane Work?
Mushroom coffee is a hot item and growing in popularity. But is it really worth the hype? There's not specific science to support any potential benefits of combining medicinal mushrooms with coffee in particular, but given that both lion's mane and caffeine are natural nootropics, it makes sense that putting the two together could have a compound effect on energy and focus*. Dose, extraction process and the purity of the mushrooms could all influence how well this brain-boosting combination may work*. Make it Yourself: DIY Mushroom Coffee RecipeHow to Get All the Benefits of Lion's Mane Mushrooms
Natural supplements work best when used consistently over time—and medicinal mushrooms are no exception. That means supplementing with Hericium erinaceus requires a little patience to see all the benefits. If positive effects don't seem evident after taking lion's mane supplements for a while, stop for a short time to see if there's any noticeable difference. The best results usually come when lion's mane is part of a regular routine.Lion's Mane Mushroom Uses
Brain health, mental clarity and focus are the top reasons why many people reach for lion's mane mushrooms*. In addition to improving mental function, Hericium erinaceus is also used for:- Reducing stress*
- Improving sleep*
- Increasing productivity*
- Supporting gut health (and, by extension, immunity)*
When to Take Lion's Mane
Is there a best time to take lion's mane mushroom*? It depends on the desired outcome. Putting mushroom powder in a morning cup of coffee or post-workout smoothie can provide a brain boost to jump start the day. Supplementing in the middle of the day can help overcome the dreaded "mid-afternoon slump"—without caffeine or sugar! Paradoxically, this brain-enhancing mushroom can also be beneficial when taken before bed. Some people find Hericium erinaceus relaxing and are able to sleep better thanks to its stress-reducing effects*. When taking lion's mane more than once per day, space the doses out. Experiment with different times to test the effects and find the most beneficial pattern for supplementation. Trouble Sleeping? Learn how taking lion's mane before bed might help.How Much Lion's Mane Mushroom Should I Take Per Day?
Medicinal mushroom dosage varies by type and form. Suggested daily doses for lion's mane are:- 0.5 - 2 gram of fruiting body extract*
- 3 grams + of fruiting body powder*
Lion's Mane Mushroom Side Effects
To date, there haven't been any human studies on whether or not Hericium erinaceus can have negative effects*. The only reported symptoms are likely the result of mushroom allergies. Animal studies show supplementing with lion's mane is apparently safe at high doses for up to one month and low-to-moderate doses for up to three months*. As a dietary supplement, the mushroom is considered safe for humans for up to 16 months*.[76] Unusual reactions to lion's mane products in people who aren't allergic to mushrooms could indicate a poor-quality product. Check the source and contents of supplements prior to beginning a regimen.How Safe are Lion's Mane Mushroom Supplements?
When obtained from reputable sources and used as advised, there's no known reason to fear side effects from taking Hericium erinaceus*. However, there are a few important considerations:- Don't supplement when pregnant or nursing
- Consult with a doctor when taking medications or dealing with specific health conditions
- Avoid taking lion's mane prior to surgery or if a bleeding disorder is present since the mushroom can slow clotting
- Monitor blood sugar for hypoglycemia when supplementing in conjunction with diabetes treatments
Is Lion's Mane Addictive?
It's reasonable to wonder if a natural "brain enhancer" has any potential addictive properties. But rest assured, it's not like a drug! Lion's mane mushroom, with its apparently low risk of side effects, is a much safer choice than synthetic nootropics*. One thing to note: Some people have reported mild psychoactive effects from taking lion's mane supplements despite the fact that the mushroom isn't a psychedelic. Erinacines can activate kappa opioid receptors, but it's unclear how or if this may affect perception at normal supplemental doses.Lion's Mane Mushroom Recipes
Because lion's mane isn't bitter like some other medicinal mushrooms, it works well as a versatile ingredient. Lion's mane powder incorporates easily into smoothies, energy bars and other homemade "functional foods" without impacting the flavor. Of course, there's no treat like fresh Hericium erinaceus, whether foraged, homegrown or store bought. It's simple to prepare and makes a delicious addition to a variety of dishes.What Does Lion's Mane Taste Like?
Ask most people this question, and you'll get a common answer: "Seafood." The light, sweet flavor of this mushroom has been likened to shellfish like crab, which explains its popularity as an ingredient in vegan "crab cake" recipes. It's not an overly fishy seafood taste—but it's just enough to fool the brain without overpowering the taste buds. Because lion's mane is soft and somewhat spongy or springy, it's great in saucy, savory dishes that have lots of spices. The mushroom soaks up the flavor and becomes even more delicious as it cooks.Is Lion's Mane Mushroom Healthy?
It's hard to find exact nutrition information for Hericium erinaceus, but the available data is similar to other culinary mushrooms. Sources show somewhere between 35 and 50 calories per 100 grams of raw mushrooms, two to four grams of protein and around seven grams of carbs (some of which is fiber). As far as the nutrient profile goes, lion's mane is a source of:- Zinc
- Potassium
- Selenium
- Polysaccharides (complex carbs with additional health benefits)
How to Cook Lion's Mane Mushroom
No special culinary prowess is required to make tasty lion's mane mushroom dishes. Here's how to have them come out perfect every time:- Brush off any dirt or gently wash and squeeze out all the excess water
- Pull apart or chop into bite-sized pieces
- Drop into a hot pan along with some onions and garlic to sauté or blacken
- Add seasonings like thyme, parsley, rosemary and/or lemon—but no liquid, or the mushrooms will get soggy
- Cook longer for a chewier texture
Fresh Ways to Use Lion's Mane Mushroom Powder
Prefer to make lion's mane a daily habit instead of an occasional treat? Try these recipes to power up your brain with supplemental powder:- Lion's Mane Matcha Latte
- Lion's "Manego" Smoothie
- Lion's Mane Energy Balls
- Brain Boosting Lion's Mane Smoothie
- Dairy-Free Queso Sauce with Lion's Mane
- The Ultimate Coffee Smoothie
- Supercharged Chocolate Bark